ARA-290 - Research Peptide for Nerve Repair and Anti-Inflammation

ARA-290, also known as Cibinetide, is an innovative research peptide derived from erythropoietin (EPO). This 11-amino acid peptide was developed to preserve the tissue-protective and anti-inflammatory properties of EPO without stimulating red blood cell production. It is used in controlled laboratory settings to investigate mechanistic analyses of inflammation, nerve repair , and organ protection.

How does ARA-290 work?

ARA-290 selectively activates the Innate Repair Receptor (IRR) complex, which consists of the EPO receptor and the β-common receptor (CD131). This receptor pathway is responsible for tissue protection, inflammation inhibition, and nerve regeneration .

In laboratory studies, ARA-290 has been shown to:

• Pro-inflammatory cytokines can decrease
• Stimulates cell survival and tissue protection
• Promotes nerve repair , especially in small fibers
• Organs such as heart, kidneys, liver and lungs can protect against oxidative stress and damage

Important: ARA-290 does not activate the classical EPO pathway for red blood cells, thus avoiding risks such as polycythemia and high blood pressure.

Benefits of ARA-290

• Supports in vitro studies of nerve repair and small nerve fiber regeneration
• Helps model anti-inflammatory signaling pathways
• Investigates organ protection in the heart, kidneys, liver and lungs
• Ideal for preclinical research into regenerative processes and tissue repair
• Promotes understanding of mechanisms behind neuropathic pain, diabetic neuropathy and autoimmune-related inflammation
• Suitable for laboratories that want to study the effects of peptides on collagen production and skin rejuvenation.

Preparation and storage

• Reconstitute ARA-290 with sterile water according to laboratory protocol
• Store in the refrigerator between 2°C and 8°C
• Protect from light and prolonged exposure to heat.
• Use vials as soon as possible after reconstitution for maximum stability.

Purity and quality

• Independently verified for >99% purity
• Each vial tested for identity, structural integrity and stability
• COA test report available for reproducible research results

Legal disclaimer

For laboratory research only. Not for human or veterinary use. The effects of ARA-290 have been studied exclusively in preclinical and in vitro models.