Ipamorelin – Research Peptide for Growth Hormone Release and Regeneration

Ipamorelin is a synthetic pentapeptide being studied in laboratory settings for its ability to stimulate natural growth hormone (GH) release. When combined with other peptides such as CJC-1295 and GHRP-6 , synergistic effects can occur that can further increase GH release. It is important to emphasize that all findings thus far are limited to preclinical research and that it is not approved for human consumption.

Benefits of Ipamoreline

• Supports Growth Hormone Release : Ipamorelin stimulates the release of GH via the ghrelin receptor, which may contribute to increased IGF-1 levels.
• Research Interest in Muscle Growth : In animal models, Ipamorelin is being investigated for its potential to promote muscle mass through increased GH and IGF-1 production.
• Supports Fat Burning : Laboratory studies suggest that Ipamorelin may contribute to fat loss through increased fat oxidation and improved insulin sensitivity.
• Research interest in skin rejuvenation : Research is underway to determine whether Ipamorelin can stimulate the production of collagen and elastin, which could potentially contribute to skin rejuvenation and anti-aging.
• Supports Tissue Repair : Ipamorelin is being studied for its potential to promote tissue repair through increased GH production.

How does Ipamorelin work?

Ipamorelin selectively binds to the ghrelin receptor (GHS-R1a) in the pituitary gland, resulting in increased growth hormone release. In laboratory settings, Ipamorelin has been shown to stimulate GH release without significantly affecting other hormones such as cortisol or prolactin.

When ipamorelin is combined with CJC-1295 , a synthetic analogue of growth hormone-releasing hormone (GHRH), synergistic effects can occur. CJC-1295 binds to the GHRH receptors in the pituitary gland, resulting in increased and sustained GH release. Together, these peptides can lead to a more consistent and sustained increase in GH levels in laboratory settings.

In addition, GHRP-6 , another growth hormone secretagogue, is being studied in combination with ipamorelin. GHRP-6 binds to the ghrelin receptor, resulting in increased GH release. Combined with ipamorelin, this can lead to an enhanced GH response in laboratory settings.

Preparation and storage

• Ipamorelin is supplied as a lyophilisate (powder) in a glass vial.
• It should be stored between 2°C and 8°C to ensure stability.
• After reconstitution (depending on buffer) shelf life 14 days.
• BAC water is always supplied for the solution.

Purity and quality

Ipamorelin comes with a Certificate of Analysis (COA) confirming purity and quality. The COA contains information on identity, purity, and potency, determined using analytical techniques such as HPLC and mass spectrometry.

Legal disclaimer

All effects of Ipamorelin are based solely on laboratory research and are not approved for human consumption . Use outside of controlled research environments is not recommended.

Want to know more?

For more information about Ipamorelin and related research, visit our Ipamorelin blog.