FOXO4-DRI Peptide – Senolytic peptide for cell renewal and tissue health
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What is FOXO4-DRI (Retro-Inverso)?
FOXO4-DRI (Retro-Inverso) is a synthetic peptide and a slightly modified version of the natural FOXO4 protein. The peptide is designed to extend the half-life and disrupt the interaction of FOXO4 with the p53 protein. This mechanism allows senescent, dysfunctional cells to undergo apoptosis and be eliminated from tissues. FOXO4-DRI is widely used in laboratory research for its potential to promote cell renewal and tissue health.
How FOXO4-DRI works according to research
FOXO4-DRI functions as a senolytic peptide that specifically targets senescent cells:
- Binds to FOXO4 and blocks interaction with p53
- Stimulates apoptosis of senescent cells without affecting healthy cells
- Supports tissue regeneration and reduces oxidative stress
- Influences cell cycle regulation and insulin sensitivity
- Promotes a healthier cellular environment in preclinical models
Through these mechanisms, FOXO4-DRI provides researchers with a powerful tool for studying biological aging and cell rejuvenation.
What are the effects of FOXO4-DRI in research?
- Selective elimination of senescent “zombie” cells in laboratory models
- Improvement of tissue function and regenerative repair
- Reduction of inflammatory markers in preclinical studies
- Potential to slow biological aging
- Support of oxidative stress balance and vital functions
⚗️ All findings are from laboratory studies. Not intended for human use.
Importance of purity and quality
Purity is crucial for reliable research results. COA test reports and HPLC analysis guarantee that peptides like FOXO4-DRI are ≥99% pure. See our FOXO4-DRI product page for lab-quality results and traceable batch numbers.
How do you store FOXO4-DRI?
- Store between 2°C and 8°C
- Protect from light and moisture to maintain stability
- Correct storage affects reproducibility and accuracy of research results
Why researchers choose FOXO4-DRI
FOXO4-DRI stands out for its senolytic properties and effect on cell renewal. The peptide is widely used in preclinical studies focused on biological aging, regenerative medicine, and tissue health. Similar peptides can be found in our other peptide blogs.
FOXO4-DRI offers researchers a powerful tool to eliminate senescent cells and stimulate cell rejuvenation. Explore our FOXO4-DRI collection, exclusively for laboratory research.